AICAR
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable nucleoside analog that is phosphorylated intracellularly to ZMP, a structural mimic of AMP. ZMP accumulation activates AMP-activated protein kinase (AMPK) without requiring changes in the adenylate energy charge, making AICAR a standard tool for dissecting AMPK-dependent signaling in cell culture. Research applications span metabolic pathway studies, mitochondrial biogenesis assays, and glucose transporter trafficking experiments. Supplied lyophilized for in vitro research use only.
Select size
$80.00
- CAS
- 2627-69-2
- MW
- 258.23 g/mol
- Formula
- C9H14N4O5
- Purity
- >=99.1 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is AICAR?
AICAR is a synthetic research compound studied in laboratory settings. It has molecular formula C9H14N4O5, a molecular weight of 258.23 g/mol, CAS 2627-69-2. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoKinetics's AICAR?
AminoKinetics supplies AICAR at >=99.1% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is AICAR supplied?
AICAR is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.