IGF-1LR3
IGF-1LR3 (Long Arg3 IGF-1) is a recombinant 83-amino acid analog of human IGF-1 carrying an N-terminal 13-residue extension and an Arg3 substitution that disrupts high-affinity binding to IGF-binding proteins. This engineering eliminates IGFBP sequestration, giving the analog 2-3x greater potency than native IGF-1 at the IGF-1 receptor in cell culture. It activates the PI3K/AKT and MAPK/ERK cascades downstream of IGF-1R, making it a high-potency research tool for studying insulin-like growth factor signaling without IGFBP interference. Supplied lyophilized for in vitro research use only.
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$65.00
- CAS
- 946870-92-4
- MW
- 9117.5 g/mol
- Formula
- C400H625N111O115S9
- Purity
- >=99.1 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is IGF-1LR3?
IGF-1LR3 is a synthetic research compound studied in laboratory settings. It has molecular formula C400H625N111O115S9, a molecular weight of 9117.5 g/mol, CAS 946870-92-4. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoKinetics's IGF-1LR3?
AminoKinetics supplies IGF-1LR3 at >=99.1% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is IGF-1LR3 supplied?
IGF-1LR3 is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.